About Previstage™ GCC Colorectal Cancer Staging Test
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The Previstage™ GCC Colorectal Cancer Staging Test is a laboratory-developed test. It was developed and its characteristics were determined by DiagnoCure Oncology Laboratories.
Previstage™ GCC is new molecular test for the staging of colorectal cancer patients. Every year in North America, 174,000 people are diagnosed with colorectal cancer, and 142,000 colorectal cancer surgeries are performed. Staging a patient with colorectal cancer is crucial because it determines the patient’s course of treatment after the surgery. Current standard of care requires that pathologists microscopically examine a thin slice of tissue from each of the lymph nodes harvested during the patient's surgery to see if cancer has spread. Currently, up to 25 - 30 percent of patients with no pathologically-positive lymph nodes (stage I and II cancers) later develop recurrent disease, presumably through occult metastases that have escaped detection. Most of these patients do not receive additional therapies such as chemotherapy. With a detection capacity that is close to 100,000 x more sensitive than microscopic methods, Previstage™ GCC provides clinicians with significantly more accurate information for staging a patient with colorectal cancer that will increase their confidence in making critical treatment decisions.
Clinical study data supports the potential for the GCC test to improve the current staging of colorectal patients. The National Cancer Institute sponsored a five-year prospective clinical trial of GCC testing in colorectal cancer patients. This study has been recently completed and the Company’s collaborators at Thomas Jefferson University are presenting the results at major medical conferences throughout the year.
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